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T Tubules

T Tubules (a term abbreviated from the their full name Transverse Tubules) are tunnel-like extensions of sarcolemma that pass through muscle fibers from one side to the other.

It is due to the side-to-side (across the muscle) orientation of these structures that they are referred to as "transverse".

T tubules play an important role in the physiology of muscle contraction:

  • Muscle action potential (that is, movement of electrical charge) travelling along T tubules trigger the release of calcium(2+) ions from the sarcoplasmic reticulum.
  • This allows the calcium (2+) ions to flood into the sarcoplasm,
  • which causes actions and movements of proteins (including actin, myosin, troponin, and tropomyosin) within the myofibrils that eventually muscle contraction.

 

 


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